- Other Names:
- neostigmin, neostigmine bromide, neostigmine methylsulfate, neostigmine metilsulfate, prostigmin, proserine, proserinum, synstigmin
- Neostigmine is a synthetic quaterenary ammonium compound which acts as an incomplete competitive inhibitor of acetylcholinesterase. It is used to treat non-depolarizing neuromuscular blocking agents. It is indicated as a treatment for curare, atropine, ivermectin, avermectins, tubocurarine, gallamine, atracurium, metocurine, pancuronium bromide, vecuronium, botulism (C. botulinum), and as a secondary agent in the treatment of coral (Micrurus spp) and cobra (Naja spp) snake bites and tetrodotoxin poisoning from porcupine fish (Diodon spp), deadly nightshade (Atropa spp), jimsonweed (Datura spp), henbane (Hyoscyamus spp), mandrake (Mandragora spp), jasmine (Cestrum spp), bittersweet (Solanum spp), and ground cherry (Chinese lantern) (Physalis spp).