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Atropine Toxicosis

Jimsonweed Poisoning

Atropine toxicosis is caused by ingestion of plants containing atropine related compounds such as Jimsonweed (Datura stramonium) and Monkshood. Atropine toxicosis can also occur due to over administering atropine medication in horses.

Toxic components
All parts of jimsonweed are poisonous--caused by tropane alkaloids. The total alkaloid content in the plant can be as high as 0.7%. Most animals will avoid it but hungry horses with little else to eat are more at risk. Jimsonweed can also get baled up in hay and served to horses in dried form, which is still toxic if consumed.

Symptoms

Rapid pulse

Dilated pupils

Rapid breathing

Restlessness

Depression

Frequent urination

Loss of appetite

Twitching

Nervousness

Weak pulse

Convulsions

Lower body temperature

Diarrhea

Diagnosis

Clinical signs
Physical exam
Laboratory tests

Support

Therapies

Therapies	Details
Supportive therapy
Activated charcoal
Physostigmine

Prevention

Make yourself aware of the weeds and plant species that can be invasive in pastures and/or poisonous to horses.
Take periodic walks around pastures to check for the presence of potentially poisonous plants
Check that hay does not contain dried up poisonous plants
If you borrow or hire farm machinery ensure it is clean prior to arriving on your property, the same goes for lending of your own equipment.
Quarantine new animals in a separate paddock the first 10 days to 2 weeks after arrival. Weed seeds can be passed through an animal's digestive tract.